Microsite es: . Grupo:

Non-invasive sensing of pH and lactate in newborns during delivery

Monday, September 23, 2019 - 11:00
Place: 
nanoGUNE seminar room, Tolosa Hiribidea 76, Donostia - San Sebastian
Who: 
Ion Olaetxea
Source Name: 
nanoGUNE

Current methods used for monitoring health status and risks of newborns during delivery do not allow either a proper, efficient or unequivocal control, resulting in a considerable raise in the awareness at social and medical level. Besides, in recent years the number of high-risk births has exponentially grown as a consequence of an increase of the age of mothers or the existence of a previous cesarean section.

During delivery, fetuses might suffer from oxygen deficiency (hypoxia). If hypoxia is prolonged, risk of cerebral palsy, hypoxic ischemic encephalopathy and neonatal mortality are severely increased. Indeed, a lack of oxygen supply activates the anaerobic metabolism of glucose, giving rise to metabolic acidosis (higher hydrogen concentration) by means of pyruvate production and a certain conversion of it to lactate.

The gold standard to identify hypoxia in fetuses is the combination of Cardiotocography (CTG) and Foetal Blood Sampling (FBS). However, this technical procedure presents a number of disadvantages: (i) It is invasive and uncomfortable for the mother; (ii) it is discontinuous; (iii) it has an important failure rate and an excessively high measurement time is required. Therefore, the development of a new sensing method integrated into a vaginal disposable probe that allows to continuously monitor pH and lactate values in a non-invasive manner represents a clinically highly desirable innovation.

x
We use third party cookies to improve our services and tailor the website to your surfing habits. By continuing to browse the site, you are agreeing to our use of cookies policy. Further information on the use of cookies.