Spin disorder in iron oxide nanoparticles: A new paradigm to elucidate for pushing the limits of magnetic hyperthermia

In recent years, the field of nanomagnetism has benefited from magnetic defects to expand the limits of knowledge and applications. However, the full potential of spin disorder is yet to be released. In this talk, I will present some of the results issued from my current MSCA-YIA project, named HYPUSH. The rationale of the project is to benefit from magnetic inhomogeneities for pushing the therapeutic efficiency of magnetic hyperthermia. For this, micromagnetic simulations and neutron diffraction are combined to elucidate the correlation between the spin arrangement and the macroscopic heat release. The aim is to identify the optimal nanoparticle designs for upgraded magnetic hyperthermia. Specifically, I will introduce and discuss the case of maghemite nanoflowers. These "multi-core" aggregates deliver an excellent heating power, but their particular switching mechanism has remained elusive. Using micromagnetic simulations, we have modeled the precise spin texture of such aggregates, identifying the role of intra-particle disorder triggering their so-called “hyperthermia sweet spot.”

Zoom: https://dipc-org.zoom.us/j/97672820029

Youtube: https://youtube.com/live/bxvI2mAdVnQ