Skip to main content
CIC nanoGUNE
  • en
  • es
  • eu

User account menu

  • Log in

Main Menu ES

  • nanoGUNE
    • At a Glance
    • Organization & Funding
    • People
    • Join us
    • Life
    • Newsroom
    • nanoPeople
  • Research
    • Research
    • Publications
    • Projects
    • External services
  • TechTransfer
    • TechTransfer
    • Start-ups
    • IP Portfolio
    • Industry collaborative research positions
    • Strategic lines
    • External services
    • News & events
  • Training
    • Master projects
    • Bachelor Final Projects
    • Summer Internships
    • Education University PHD
  • Society

User menu

  • Log in
  1. Home
  2. Projects
  3. NANOANTENNA - Development of a high sensitive and specific nanobiosensor based on surface enhanced vibrational spectroscopy dedicated to the in vitro proteins detection and disease diagnosis

NANOANTENNA - Development of a high sensitive and specific nanobiosensor based on surface enhanced vibrational spectroscopy dedicated to the in vitro proteins detection and disease diagnosis

Funding Program
EU - FP7
Coordinator
Centre national de la Recherche Scientifique CNRS - France
Call
FP7-HEALTH-2009-single-stage
Project ID
241818
PI at nanoGUNE
Rainer Hillenbrand (r.hillenbrand@nanogune.eu)
From
01/10/2009
To
31/03/2013
Total funding
5 920 214,52€
Web
https://cordis.europa.eu/project/rcn/92196_en.html
Research group
Nanooptics

The main goal of our proposal is to develop a novel optical nanobiosensor based on extraordinary vibrational signal enhancement of the proteins to be detected. To reach vibrational signal enhancement, we will exploit the optical properties of specially designed metallic nanoparticles which should act as nanoantenna and the associated field enhancement to obtain a direct detection of proteins bound to the nanoparticle. Thus, our sensor will reach high sensitivity provided by the recently established large enhancement of vibration signals due to the resonant excitation of the nanoantenna device used as substrates. The aim is to detect only a few proteins with concentration much lower than 1pM and finally to reach detection threshold such as femtomole or lower. High molecular selectivity will be reached with the functionalisation of the nanoantenna. Such functionalisation will selectively favour the immobilisation of the protein to be detected at the vicinity of the nanoparticle surface, providing the best enhancement and then the detection of the targeted protein. Our nanobiosensor will include two main components: the nanoantenna device which corresponds to our sensor transducer and the functionalisation which corresponds to its bioreceptor. And then, each functionalised nanoantenna device used as vibrational signal enhanced system is an individual and specific nanosensor of proteins. As a consequence, our nanobiosensor integrated in a vibrational spectroscope will allow the detection and the analysis of the enhanced vibrational signal from the targeted proteins and thus corresponds to our diagnosis instrument. Our nanobiosensor will be validated on the detection of proteins on body fluids.These proteins have been chosen since they have been identified as specific biomarkers of common pathologies. This validation will be applied it to improve their detection (better sensitivity, decrease of the detection threshold) and open the way to the early diagnosis

Partners

Centre national de la Recherche Scientifique CNRS - France (Coordinator)

Agencia Estatal Consejo Superior de Investigaciones Científicas-Spain

Institut National de la Sante et de la recherche medicale -France

Ruprecht-Karls-Universitaet Heidelberg -Germany

Consiglio Nazionale delle Ricerche -Italy

Ben-Gurion University of the Negev -Israel

CIC nanoGUNE -Spain

Fondazione Istituto Italiano di Tecnologia - Italy

Horibe France SAS -France

CIC biomaGUNE -Spain

Universite de Technologie de Troyes -France

Technoclone Herstellung Diagnostikaund Arzneimitteln GMBH - Vienna

  • whatsapp
  • facebook
  • twitter
  • linkedin
  • print

By funding program

  • - Any -
  • ERA.NET
  • EU - FP7
  • European Commission
  • EU - Horizon Europe
  • EU - Horizon 2020
  • FET Open
  • Initial Training Network (ITN)
  • MSCA - Individual Fellowship
  • Spanish Government
  • CIC nanoGUNE
  • Tolosa Hiribidea, 76
  • E-20018 Donostia / San Sebastian
  • +34 943 574 000 · nano@nanogune.eu
  • Facebook Twitter Youtube Linkedin Instagram Subscribe to our Newsletter

Menú pie principal

  • nanoGUNE
  • Research
  • TechTransfer
  • Training
  • Society
  • nanoPeople

Menú pie servicios

  • External services
  • Publications
  • Seminars
  • Join us
  • Newsroom
  • Contractor profile
  • Corporate Compliance

Menú pie grupos

  • Nanomagnetism
  • Nanooptics
  • Self Assembly
  • Nanobiosystems
  • Nanodevices
  • Electron Microscopy

Menú pie grupos 2

  • Theory
  • Nanomaterials
  • Quantum-Probe Microscopy
  • Nanoengineering
  • Quantum Hardware

Funded by

  • EJ/GV
  • Diputación
  • FEDER
  • FEDER
  • Ministerio de Ciencia e Innovación

Member of

  • BRTA
  • SOMM

Distinctions

  • Distinción de Excelencia María de Maeztu 2022-2025
  • Excellence Research
  • UNE-166002

Menú legales

  • Accesibility
  • Legal notice
  • Privacy policy
  • Cookies policy
  • Confidentiality policy
by ACC