Spectral Signatures to Biomonitoring: Mapping Industrial Opportunities

Early in my career, I was given the fascinating challenge of transforming complex spectral fingerprints into meaningful biological insights (1). This journey took me from uncovering hidden cross-talk communication in cancer microenvironments (2) to developing novel quality control methods in bioprocesses (3). In this talk, I will revisit some of my past findings, connect them with present opportunities, and sketch a vision of a future now taking shape, one where the rise of AI and the shift toward Biopharma 4.0 open fresh opportunities for turning light into lasting impact.   1. ‎Seeing beyond Labels: Optical Technologies Reshaping Cell Culture Monitoring in Biomedicine. ACS Applied Engineering Materials. 2024 2 (12), 2790-2814 2. SERS analysis of cancer cell-secreted purines reveals a unique paracrine crosstalk in MTAP-deficient tumors. Proceedings of the National Academy of Sciences. 2023 120 (52), e2311674120. 3.Machine learning‐assisted high‐throughput SERS classification of cell secretomes. Small. 2023 19 (51), 2207658.